When symptoms first began I was on Prozac, Seroquel, Ambien, and Xanax. Then I quit the seroquel and was put on Wellbutrin along with the Prozac. The prozac made my sucidal ideation worse and I really didn't feel it worked well (besides the absolute inability to orgasm). The Xanax worked great for anxiety, but is highly addictive. Eventually, I was only prescribed Wellbutrin at 300mgs and I take Melatonin at night for sleep. For now, that is where I am at. I tried to quit the Wellbutrin and slid back into depression and I have no adverse side effects from taking it, so I will continue to do so until doctor says to get off. For right now, it works for me.